Search results for "Clinical history"

showing 10 items of 15 documents

Reply to Drs. Kiaei and Molinaro Regarding the Publication “Comparison of a Bridge Immunoassay with Two Bioassays for Thyrotropin Receptor Antibody D…

2020

Dear Editor,Drs. Kiaei and Molinaro 1 put forth two criticisms of the manuscript published by us 2. They state that the experimental design of this study is flawed and that the authors falsely claim that negative Thyretain™ TSI Reporter BioAssay results for two Graves’ diseases patients undergoing drug treatments means the absence of stimulating antibodies. To substantiate this claim Drs. Kiaei and Molinaro point out that the manufacturer of the Thyretain TSI Reporter BioAssay clearly states in the package insert that “[t]he effects of various drug therapies on the performance of this Kit have not been established” 1. Second, the package insert explicitly states that “[a] negative result do…

medicine.medical_specialtyLetter to the editorPackage insertEndocrinology Diabetes and MetabolismClinical BiochemistryThyrotropin receptor Antibody030209 endocrinology & metabolismBiochemistryAntibodies03 medical and health sciences0302 clinical medicineEndocrinologyClinical historyInternal medicineClinical informationHumansMedicineBioassayLetter to the EditorImmunoassaymedicine.diagnostic_testbusiness.industryBiochemistry (medical)Receptors ThyrotropinGeneral MedicineGraves DiseasePatient population030220 oncology & carcinogenesisImmunoassaybusinessImmunoglobulins Thyroid-StimulatingHormone and Metabolic Research
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Differentiation between brain metastases and glioblastoma multiforme based on MRI, MRS and MRSI

2009

Brain metastases and glioblastoma multiforme are the most aggressive and common brain tumours in adults and they require a different clinical management. Anatomical magnetic resonance imaging (MRI) or clinical history, cannot always clearly distinguish between them. This study describes and verifies the use of magnetic resonance spectroscopy (MRS) and magnetic resonance spectroscopic imaging (MRSI) in combination with MRI for differential diagnosis of glioblastomas and metastases. Feature selection methods are applied to the magnetic resonance (MR) spectra of 121 patients and relevant features are detected. Different classification methods are used to distinguish glioblastoma multiforme and…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryMagnetic resonance spectroscopic imagingMagnetic resonance imagingmedicine.diseaseMetastasisClinical historymedicineRadiologyDifferential diagnosisMr imagesbusinessBrain metastasisGlioblastoma
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Rhinomanometry: point of care test (POCT) for allergic rhinitis in children?

2021

Allergic rhinitis (AR) is a global health problem: its prevalence is 23% in Europe, although it is underestimated because as many as 45% of the cases remain undiagnosed. Globally, almost 500 million people suffer from AR, which shows its increasing incidences. The diagnostic course of AR is based on clinical history, supported by anterior rhinoscopy. This inspects the anterior part of the nasal cavity accompanied by allergic sensitivity tests (cutaneous allergic skin tests or specific immunoglobulin E levels). The availability of standardised diagnostic proceduresis able to provide objective evaluations of inflammatory situation, and the degree of nasal obstruction may give an advantage in …

Pulmonary and Respiratory MedicineNasal cavitymedicine.medical_specialtymedicine.diagnostic_testSpecific immunoglobulin Ebusiness.industryPoint-of-care testingImmunologyGeneral Medicinemedicine.anatomical_structureClinical historymedicineImmunology and AllergyNarrative reviewIn patientObjective evaluationRhinomanometryIntensive care medicinebusinessAllergologia et Immunopathologia
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Trouble always comes in threes: three mutations for three auto inflammatory genes in a child and in his father

2014

The coexistence of mutations in more than one gene, linked to Autoinflammatory Diesases, can confuse and make difficult the diagnosis and management of these patients, especially in childhood, when the clinical history is still brief.

Pediatricsmedicine.medical_specialtyauto inflammatory geneBioinformaticsSettore MED/38 - Pediatria Generale E SpecialisticaRheumatologyClinical historyInternal medicinemedicineImmunology and AllergyPediatrics Perinatology and Child HealthGeneInflammatory genesHeterozygous mutationgene mutationsbusiness.industryMultiple sclerosisfood and beveragesmedicine.diseaseRheumatologyPharyngitisCanakinumabPediatrics Perinatology and Child HealthPoster Presentationmedicine.symptombusinessmedicine.drug
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Valoración funcional en pacientes intervenidos mediante plastia de LCA con semitendinoso-recto interno y sistema Togglelock.

2020

espanolIntroduccion: Una de las lesiones mas frecuente de la rodilla y que esta en aumento, sobre todo en el ambito deportivo es la lesion del ligamento cruzado anterior. La reconstruccion quirurgica es fundamental para recuperar la biomecanica de la rodilla, proporcionar una correcta estabilidad y funcionamiento libre de dolor, asi como evitar cambios degenerativos tempranos. El objetivo del presente estudio fue valorar la recuperacion funcional de los pacientes sometidos a una reconstruccion del ligamento cruzado anterior mediante ligamentoplastia con tendon semitendinoso-recto interno y sistema Toggelock. Material y metodos: Se diseno un estudio retrospectivo descriptivo observacional, e…

Pharmacologymedicine.anatomical_structureClinical historybusiness.industryAnterior cruciate ligamentmedicineMean ageTibial fractureAssessment scaleKnee injuriesFunctional recoverybusinessNuclear medicineRevista Española de Cirugía Osteoarticular
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Anomalous Origin and Course of the Right Coronary Artery

2006

Coronary anomalous origin from the wrong aortic sinus has been thought to be a risk factor for ischemia because of acute takeoff from the aorta and flow between the aorta and the pulmonary artery.1–4 A 30-year-old man suddenly died within an hour of waking. His clinical history revealed no evidence of any disease, and the postmortem toxicological examination was negative. Autopsy ruled out violent or natural noncardiac causes …

medicine.medical_specialtyAortabusiness.industryIschemiaAutopsymedicine.diseasemedicine.anatomical_structureClinical historyPhysiology (medical)Internal medicineRight coronary arterymedicine.arteryAortic sinusAnesthesiacardiovascular systemmedicineCardiologyRisk factorCardiology and Cardiovascular MedicinebusinessCirculation
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Impact of the BioFire FilmArray gastrointestinal panel on patient care and infection control.

2020

Contains fulltext : 218876.pdf (Publisher’s version ) (Open Access) OBJECTIVES: Conventional routine PCR testing for gastrointestinal infections is generally based on pathogen related panels specifically requested by clinicians and can be erroneous and time consuming. The BioFire FilmArray gastrointestinal (GI) panel combines 22 pathogens into a single cartridge-based test on a random-access system, thereby reducing the turnaround time to less than 2 hours. We described the clinical impact of implementing the BioFire FilmArray on patients with gastroenteritis in our hospital. METHODS: Patients attending a Dutch tertiary care center (Radboud University Medical Center), from whom stool sample…

0301 basic medicineMaleTime Factorslnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Pathology and Laboratory MedicineTertiary carePolymerase Chain ReactionTertiary Care CentersFeces0302 clinical medicineClinical historyAntibioticsMedicine and Health SciencesMedicineInfection controlUniversity medicalGastrointestinal Infections030212 general & internal medicineChildNetherlandsAged 80 and overPotential impactMultidisciplinaryWomen's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17]AntimicrobialsQRDrugsGastrointestinal AnalysisMiddle AgedGastroenteritisBacterial PathogensBioassays and Physiological AnalysisMolecular Diagnostic TechniquesMedical MicrobiologyChild PreschoolViral PathogensVirusesMedicinePathogensResearch ArticleAdultmedicine.medical_specialtyIsolation (health care)AdolescentClostridium DifficileScience030106 microbiologyGastroenterology and HepatologyResearch and Analysis MethodsMicrobiologyPatient care03 medical and health sciencesYoung AdultDiagnostic MedicineInternal medicineMicrobial ControlHumansMicrobial PathogensAgedPharmacologyInfection ControlBacteriabusiness.industryGut BacteriaInfant NewbornOrganismsInfantBiology and Life SciencesPatient datalnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]Patient CarebusinessPloS one
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Dizziness and vertigo in a department of emergency medicine.

1995

Dizziness is a common and vexing diagnostic problem in emergency departments. The term is rather undefinite and often misused, but can in practice be classified into four categories: fainting, disequilibrium, vertigo and miscellaneous syndromes. Vertigo is the most common category of dizziness. Classification of vertigo can be based either on chronological criteria (acute, recurrent or chronic vertigo) or on topographical criteria (peripheral or central vertigo). Physicians working in emergency departments must be able to rapidly identify patients with potentially serious forms of vertigo, which could cause death or disability, and patients with mild conditions, that can be effectively trea…

Chronic vertigoMalemedicine.medical_specialtySedationPhysical examinationDiseaseNystagmusFaintingDizzinessDiagnosis DifferentialClinical historyVertigootorhinolaryngologic diseasesmedicineHumansSyphilisEar DiseasesPhysical Examinationbiologymedicine.diagnostic_testbusiness.industrybiology.organism_classificationEmergency medicineEmergency MedicineVertigoFemalemedicine.symptomNervous System DiseasesbusinessEmergency Service HospitalAlgorithmsEuropean journal of emergency medicine : official journal of the European Society for Emergency Medicine
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Surgery-triggered and non surgery-triggered Bisphosphonate-related Osteonecrosis of the Jaws (BRONJ): A retrospective analysis of 567 cases in an Ita…

2011

Invasive local procedures are often reported in clinical history of patients suffering from Bisphosphonates-Related Osteonecrosis of the Jaws (BRONJ) but over 40% of spontaneous forms have been also described in literature. We compared age, gender, underlying bone disorders, bisphosphonate therapy, clinical features and surgical outcome of 205 cases (36.2%) of BRONJ non surgery-triggered (group 1) with 362 (63.8%) cases of surgery-triggered forms (group 2). Differences between group 1 and 2 were analysed using Mann-Whitney U and χ2 tests. Statistical analysis was performed using STATA 8. Zoledronate was the most used type of bisphosphonate (63.4% versus 69.0%) and the mandible was the most …

AdultMaleCancer Researchmedicine.medical_specialtyTooth extractionmedicine.medical_treatmentZoledronic AcidSettore MED/28 - Malattie OdontostomatologicheRisk FactorsClinical historySpontaneous formmedicineRetrospective analysisHumansStatistical analysisStage (cooking)AgedRetrospective StudiesAged 80 and overSurgical outcomeBone Density Conservation AgentsDiphosphonatesBRONJOrthognathic Surgical Proceduresbusiness.industryImidazolesOsteonecrosisBisphosphonates-related Osteonecrosis of the JawMiddle AgedBisphosphonateSurgeryZoledronic acidItalyOncologyMulticenter studyFemaleBisphosphonate therapyOral SurgerybusinessJaw Diseasesmedicine.drugOral Oncology
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Criteria deemed important by the relatives for designating a reference person for patients hospitalized in ICU

2020

Abstract Purpose We investigated the criteria that patients' relatives deem important for choosing, among themselves, the person best qualified to interact with the caregiving staff. Methods Exploratory, observational, prospective, multicentre study between 1st March and 31st October 2018 in 2 intensive care units (ICUs). A 12-item questionnaire was completed anonymously by family members of patients hospitalized in the ICU 3 and 5 days after the patient's admission. Relatives were eligible if they understood French and if no surrogate had been appointed by the patient prior to ICU admission. More than one relative per patient could participate. Results In total, 87 relatives of 73 patients…

AdultMalemedicine.medical_specialtyCritical Care[SDV]Life Sciences [q-bio]Decision MakingEmotionsCritical Care and Intensive Care MedicineProxy (climate)law.invention03 medical and health sciences0302 clinical medicineClinical historylawSurveys and QuestionnairesIntensive careHumansMedicineFamilyProspective StudiesAgedbusiness.industry030208 emergency & critical care medicineMiddle AgedIntensive care unitIcu admissionHospitalizationIntensive Care UnitsFamily memberCaregivers030228 respiratory systemSpouseFamily medicineFemaleObservational studyFamily RelationsbusinessJournal of Critical Care
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